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Laminin γ1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve
Laminins are heterotrimeric extracellular matrix proteins that regulate cell viability and function. Laminin-2, composed of α2, β1, and γ1 chains, is a major matrix component of the peripheral nervous system (PNS). To investigate the role of laminin in the PNS, we used the Cre–loxP system to disrupt...
Autores principales: | Chen, Zu-Lin, Strickland, Sidney |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173689/ https://www.ncbi.nlm.nih.gov/pubmed/14638863 http://dx.doi.org/10.1083/jcb.200307068 |
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