Breathing down the neck of Unc104

The Unc104/Kif1A class of kinesins transports synaptic vesicle precursors along microtubules with high speed and processivity that has been proposed to depend on reversible dimerization between two poorly motile monomers. In this issue, Al-Bassam et al. (2003) discover a structural basis for regulat...

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Detalles Bibliográficos
Autor principal: Wordeman, Linda
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173696/
https://www.ncbi.nlm.nih.gov/pubmed/14638852
http://dx.doi.org/10.1083/jcb.200310137
Descripción
Sumario:The Unc104/Kif1A class of kinesins transports synaptic vesicle precursors along microtubules with high speed and processivity that has been proposed to depend on reversible dimerization between two poorly motile monomers. In this issue, Al-Bassam et al. (2003) discover a structural basis for regulation of motility by reversible dimerization.

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