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Cup-ling oskar RNA localization and translational control

RNA localization and spatially restricted translational control can serve to deploy specific proteins to particular places within a cell. oskar (osk) RNA is a key initiatior of posterior patterning and germ cell specification in Drosophila, and its localization and translation are under elaborate co...

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Detalles Bibliográficos
Autor principal: Lasko, Paul
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173710/
https://www.ncbi.nlm.nih.gov/pubmed/14691130
http://dx.doi.org/10.1083/jcb.200311123
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author Lasko, Paul
author_facet Lasko, Paul
author_sort Lasko, Paul
collection PubMed
description RNA localization and spatially restricted translational control can serve to deploy specific proteins to particular places within a cell. oskar (osk) RNA is a key initiatior of posterior patterning and germ cell specification in Drosophila, and its localization and translation are under elaborate control. In this issue, Wilhelm et al. (2003) show that the protein Cup both promotes osk localization and participates in repressing translation of unlocalized osk.
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spelling pubmed-21737102008-05-01 Cup-ling oskar RNA localization and translational control Lasko, Paul J Cell Biol Comment RNA localization and spatially restricted translational control can serve to deploy specific proteins to particular places within a cell. oskar (osk) RNA is a key initiatior of posterior patterning and germ cell specification in Drosophila, and its localization and translation are under elaborate control. In this issue, Wilhelm et al. (2003) show that the protein Cup both promotes osk localization and participates in repressing translation of unlocalized osk. The Rockefeller University Press 2003-12-22 /pmc/articles/PMC2173710/ /pubmed/14691130 http://dx.doi.org/10.1083/jcb.200311123 Text en Copyright © 2003, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Comment
Lasko, Paul
Cup-ling oskar RNA localization and translational control
title Cup-ling oskar RNA localization and translational control
title_full Cup-ling oskar RNA localization and translational control
title_fullStr Cup-ling oskar RNA localization and translational control
title_full_unstemmed Cup-ling oskar RNA localization and translational control
title_short Cup-ling oskar RNA localization and translational control
title_sort cup-ling oskar rna localization and translational control
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173710/
https://www.ncbi.nlm.nih.gov/pubmed/14691130
http://dx.doi.org/10.1083/jcb.200311123
work_keys_str_mv AT laskopaul cuplingoskarrnalocalizationandtranslationalcontrol