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Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ–σ1 and AP-3 δ–σ3 hemicomplexes

The sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present in the cytosolic tails of the proteins. A subset of these signals conform to the [DE]XXXL[LI] consensus motif and mediate sorting via interactions with heterotetrameric adaptor protein (AP) complexes. How...

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Detalles Bibliográficos
Autores principales:	Janvier, Katy, Kato, Yukio, Boehm, Markus, Rose, Jeremy R., Martina, José A., Kim, Bong-Yoon, Venkatesan, Sundararajan, Bonifacino, Juan S.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173715/ https://www.ncbi.nlm.nih.gov/pubmed/14691137 http://dx.doi.org/10.1083/jcb.200307157

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