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TGFβ(3) signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

Epithelial mesenchymal transformation (EMT) of the medial edge epithelial (MEE) seam creates palatal confluence. This work aims to elucidate the molecular mechanisms by which TGFβ(3) brings about palatal seam EMT. We collected mRNA for PCR analysis from individual transforming MEE cells by laser mic...

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Detalles Bibliográficos
Autores principales: Nawshad, Ali, Hay, Elizabeth D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173726/
https://www.ncbi.nlm.nih.gov/pubmed/14691138
http://dx.doi.org/10.1083/jcb.200306024