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Spindle checkpoint proteins Mad1 and Mad2 are required for cytostatic factor–mediated metaphase arrest

In cells containing disrupted spindles, the spindle assembly checkpoint arrests the cell cycle in metaphase. The budding uninhibited by benzimidazole (Bub) 1, mitotic arrest-deficient (Mad) 1, and Mad2 proteins promote this checkpoint through sustained inhibition of the anaphase-promoting complex/cy...

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Detalles Bibliográficos
Autores principales:	Tunquist, Brian J., Eyers, Patrick A., Chen, Lin G., Lewellyn, Andrea L., Maller, James L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173727/ https://www.ncbi.nlm.nih.gov/pubmed/14691134 http://dx.doi.org/10.1083/jcb.200306153

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