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Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the β(2)-adrenergic receptor
cAMP controls many cellular processes mainly through the activation of protein kinase A (PKA). However, more recently PKA-independent pathways have been established through the exchange protein directly activated by cAMP (Epac), a guanine nucleotide exchange factor for the small GTPases Rap1 and Rap...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173739/ https://www.ncbi.nlm.nih.gov/pubmed/12578910 http://dx.doi.org/10.1083/jcb.200209105 |