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Regulation of the formation of osteoclastic actin rings by proline-rich tyrosine kinase 2 interacting with gelsolin
Osteoclast activation is important for bone remodeling and is altered in multiple bone disorders. This process requires cell adhesion and extensive actin cytoskeletal reorganization. Proline-rich tyrosine kinase 2 (PYK2), a major cell adhesion–activated tyrosine kinase in osteoclasts, plays an impor...
Autores principales: | Wang, Qiang, Xie, Yi, Du, Quan-Sheng, Wu, Xiao-Jun, Feng, Xu, Mei, Lin, McDonald, Jay M., Xiong, Wen-Cheng |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173747/ https://www.ncbi.nlm.nih.gov/pubmed/12578912 http://dx.doi.org/10.1083/jcb.200207036 |
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