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Polarized growth and organelle segregation in yeast: the tracks, motors, and receptors
In yeast, growth and organelle segregation requires formin-dependent assembly of polarized actin cables. These tracks are used by myosin Vs to deliver secretory vesicles for cell growth, organelles for their segregation, and mRNA for fate determination. Several specific receptors have been identifie...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173777/ https://www.ncbi.nlm.nih.gov/pubmed/12642608 http://dx.doi.org/10.1083/jcb.200301035 |
| Sumario: | In yeast, growth and organelle segregation requires formin-dependent assembly of polarized actin cables. These tracks are used by myosin Vs to deliver secretory vesicles for cell growth, organelles for their segregation, and mRNA for fate determination. Several specific receptors have been identified that interact with the cargo-binding tails of the myosin Vs. A recent study implicates specific degradation in the bud of the vacuolar receptor, Vac17, as a mechanism for cell cycle–regulated segregation of this organelle. |
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