Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration

Întegrins coordinate spatial signaling events essential for cell polarity and directed migration. Such signals from α4 integrins regulate cell migration in development and in leukocyte trafficking. Here, we report that efficient α4-mediated migration requires spatial control of α4 phosphorylation by...

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Detalles Bibliográficos
Autores principales: Goldfinger, Lawrence E., Han, Jaewon, Kiosses, William B., Howe, Alan K., Ginsberg, Mark H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173787/
https://www.ncbi.nlm.nih.gov/pubmed/12913113
http://dx.doi.org/10.1083/jcb.200304031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173787/
https://www.ncbi.nlm.nih.gov/pubmed/12913113
http://dx.doi.org/10.1083/jcb.200304031

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