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Unique targeting of cytosolic phospholipase A(2) to plasma membranes mediated by the NADPH oxidase in phagocytes
Cytosolic phospholipase A(2) (cPLA(2))–generated arachidonic acid (AA) has been shown to be an essential requirement for the activation of NADPH oxidase, in addition to its being the major enzyme involved in the formation of eicosanoid at the nuclear membranes. The mechanism by which cPLA(2) regulat...
Autores principales: | Shmelzer, Zeev, Haddad, Nurit, Admon, Ester, Pessach, Itai, Leto, Thomas L., Eitan-Hazan, Zahit, Hershfinkel, Michal, Levy, Rachel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2003
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173789/ https://www.ncbi.nlm.nih.gov/pubmed/12913107 http://dx.doi.org/10.1083/jcb.200211056 |
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