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Gene expression during ER stress–induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

Endoplasmic reticulum (ER) stress has been implicated in the pathogenesis of ischemic and neurodegenerative disorders. Treatment of human SH-SY5Y neuroblastoma cells with tunicamycin, an inhibitor of protein glycosylation, rapidly induced the expression of target genes of the unfolded protein respon...

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Detalles Bibliográficos
Autores principales:	Reimertz, Claus, Kögel, Donat, Rami, Abdelhaq, Chittenden, Thomas, Prehn, Jochen H.M.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173793/ https://www.ncbi.nlm.nih.gov/pubmed/12913114 http://dx.doi.org/10.1083/jcb.200305149

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