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Phosphatidylinositol phosphate 5-kinase Iβ recruits AP-2 to the plasma membrane and regulates rates of constitutive endocytosis

Overexpression of phosphatidylinositol phosphate 5-kinase (PIP5KI) isoforms α, β, or γ in CV-1 cells increased phosphatidylinositol 4,5-bisphosphate (PIP2) levels by 35, 180, and 0%, respectively. Endocytosis of transferrin receptors, association of AP-2 proteins with membranes, and the number of cl...

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Detalles Bibliográficos
Autores principales: Padrón, David, Wang, Ying Jie, Yamamoto, Masaya, Yin, Helen, Roth, Michael G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173809/
https://www.ncbi.nlm.nih.gov/pubmed/12913109
http://dx.doi.org/10.1083/jcb.200302051