Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship

Studies of the cell invasion mechanism of the parasite Trypanosoma cruzi led to a series of novel findings, which revealed a previously unsuspected ability of conventional lysosomes to fuse with the plasma membrane. This regulated exocytic process, previously regarded mostly as a specialization of c...

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Detalles Bibliográficos
Autor principal: Andrews, Norma W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Mini-Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173812/
https://www.ncbi.nlm.nih.gov/pubmed/12147679
http://dx.doi.org/10.1083/jcb.200205110
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author Andrews, Norma W.
author_facet Andrews, Norma W.
author_sort Andrews, Norma W.
collection PubMed
description Studies of the cell invasion mechanism of the parasite Trypanosoma cruzi led to a series of novel findings, which revealed a previously unsuspected ability of conventional lysosomes to fuse with the plasma membrane. This regulated exocytic process, previously regarded mostly as a specialization of certain cell types, was recently shown to play an important role in the mechanism by which cells reseal their plasma membrane after injury.
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spelling pubmed-21738122008-05-01 Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship Andrews, Norma W. J Cell Biol Mini-Reviews Studies of the cell invasion mechanism of the parasite Trypanosoma cruzi led to a series of novel findings, which revealed a previously unsuspected ability of conventional lysosomes to fuse with the plasma membrane. This regulated exocytic process, previously regarded mostly as a specialization of certain cell types, was recently shown to play an important role in the mechanism by which cells reseal their plasma membrane after injury. The Rockefeller University Press 2002-08-05 /pmc/articles/PMC2173812/ /pubmed/12147679 http://dx.doi.org/10.1083/jcb.200205110 Text en Copyright © 2002, The Rockefeller University Press This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Mini-Reviews
Andrews, Norma W.
Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title_full Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title_fullStr Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title_full_unstemmed Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title_short Lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
title_sort lysosomes and the plasma membrane: trypanosomes reveal a secret relationship
topic Mini-Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173812/
https://www.ncbi.nlm.nih.gov/pubmed/12147679
http://dx.doi.org/10.1083/jcb.200205110
work_keys_str_mv AT andrewsnormaw lysosomesandtheplasmamembranetrypanosomesrevealasecretrelationship

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