Cargando…

Distinct cell death pathways triggered by the adenovirus early region 4 ORF 4 protein

In transformed cells, induction of apoptosis by adenovirus type 2 (Ad2) early region 4 ORF 4 (E4orf4) correlates with accumulation of E4orf4 in the cell membrane–cytoskeleton fraction. However, E4orf4 is largely expressed in nuclear regions before the onset of apoptosis. To determine the relative co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Robert, Amélie, Miron, Marie-Joëlle, Champagne, Claudia, Gingras, Marie-Claude, Branton, Philip E., Lavoie, Josée N.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173819/ https://www.ncbi.nlm.nih.gov/pubmed/12163473 http://dx.doi.org/10.1083/jcb.200201106

Ejemplares similares

Adenovirus E4 Open Reading Frame 4–Induced Apoptosis Involves Dysregulation of Src Family Kinases
por: Lavoie, Josée N., et al.
Publicado: (2000)

E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk
por: Lavoie, Josée N., et al.
Publicado: (1998)

Identification of the Adenovirus E4orf4 Protein Binding Site on the B55α and Cdc55 Regulatory Subunits of PP2A: Implications for PP2A Function, Tumor Cell Killing and Viral Replication
por: Mui, Melissa Z., et al.
Publicado: (2013)

Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death
por: Dziengelewski, Claire, et al.
Publicado: (2020)

The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Enhances E1A Functional Activity
por: Dallaire, Frédéric, et al.
Publicado: (2015)

Mechanisms of Cancer Cell Killing by the Adenovirus E4orf4 Protein
por: Kleinberger, Tamar
Publicado: (2015)

The adenovirus E4orf4 protein induces a unique mode of cell death while inhibiting classical apoptosis
por: Pechkovsky, Antonina, et al.
Publicado: (2013)

Mechanism of Adenovirus E4-ORF3-Mediated SUMO Modifications
por: Sohn, Sook-Young, et al.
Publicado: (2019)

The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F
por: Dallaire, Frédéric, et al.
Publicado: (2015)

The Adenovirus E4orf4 Protein Provides a Novel Mechanism for Inhibition of the DNA Damage Response
por: Brestovitsky, Anna, et al.
Publicado: (2016)

Impact of Adenovirus E4-ORF3 Oligomerization and Protein Localization on Cellular Gene Expression
por: Vink, Elizabeth I., et al.
Publicado: (2015)

Effects of the Deletion of Early Region 4 (E4) Open Reading Frame 1 (orf1), orf1-2, orf1-3 and orf1-4 on Virus-Host Cell Interaction, Transgene Expression, and Immunogenicity of Replicating Adenovirus HIV Vaccine Vectors
por: Thomas, Michael A., et al.
Publicado: (2013)

E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses
por: Sangare, Kotou, et al.
Publicado: (2022)

The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes
por: Brestovitsky, Anna, et al.
Publicado: (2011)

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix- associated PML bodies
Publicado: (1995)

Selective elimination of cancer cells by the adenovirus E4orf4 protein in a Drosophila cancer model: a new paradigm for cancer therapy
por: Rosen, Helit, et al.
Publicado: (2019)

The Adenovirus E4-ORF3 Protein Stimulates SUMOylation of General Transcription Factor TFII-I to Direct Proteasomal Degradation
por: Bridges, Rebecca G., et al.
Publicado: (2016)

Cisplatin Relocalizes RNA Binding Protein HuR and Enhances the Oncolytic Activity of E4orf6 Deleted Adenovirus
por: Habiba, Umma, et al.
Publicado: (2020)

Adenovirus E4orf4 protein induces PP2A-dependent growth arrest in Saccharomyces cerevisiae and interacts with the anaphase-promoting complex/cyclosome
por: Kornitzer, Daniel, et al.
Publicado: (2001)

Hepatic Expression of Adenovirus 36 E4ORF1 Improves Glycemic Control and Promotes Glucose Metabolism Through AKT Activation
por: McMurphy, Travis B., et al.
Publicado: (2017)

The Human Adenovirus E4-ORF1 Protein Subverts Discs Large 1 to Mediate Membrane Recruitment and Dysregulation of Phosphatidylinositol 3-Kinase
por: Kong, Kathleen, et al.
Publicado: (2014)

Analysis of Fowl Adenovirus 4 Transcriptome by De Novo ORF Prediction Based on Corrected Nanopore Full-Length cDNA Sequencing Data
por: Lu, Zhuozhuang, et al.
Publicado: (2023)

Adenovirus E4orf6 targets pp32/LANP to control the fate of ARE-containing mRNAs by perturbing the CRM1-dependent mechanism
por: Higashino, Fumihiro, et al.
Publicado: (2005)

Characterization of BoHV-4 ORF45
por: Russo, Luca, et al.
Publicado: (2023)

COVID-19 adenovirus vaccine triggers antibodies against PF4 complexes to activate complement and platelets
por: Pitkänen, Hanna H., et al.
Publicado: (2021)

Activation of immune receptor Rx1 triggers distinct immune responses culminating in cell death after 4 hours
por: Knip, Marijn, et al.
Publicado: (2019)

Multiple Functions for ORF75c in Murid Herpesvirus-4 Infection
por: Gaspar, Miguel, et al.
Publicado: (2008)

The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
por: Yang, Yang, et al.
Publicado: (2013)

Apoptosis Triggered by ORF3 Proteins of the Circoviridae Family
por: Zhang, Yanting, et al.
Publicado: (2021)

orf137 triggers cytoplasmic male sterility in tomato
por: Kuwabara, Kosuke, et al.
Publicado: (2022)

Orf virus DNA prime-protein boost strategy is superior to adenovirus-based vaccination in mice and sheep
por: Wang, Yan, et al.
Publicado: (2023)

Bovine coronaviruses associated with enteric and respiratory diseases in Canadian dairy cattle display different reactivities to anti-HE monoclonal antibodies and distinct amino acid changes in their HE, S and ns4.9 protein
por: Gélinas, Anne-Marie, et al.
Publicado: (2001)

Canine Adenovirus 2: A Natural Choice for Brain Circuit Dissection
por: Lavoie, Andréanne, et al.
Publicado: (2020)

Effect of probiotic bacteria on porcine rotavirus OSU infection of porcine intestinal epithelial IPEC-J2 cells
por: Leblanc, Danielle, et al.
Publicado: (2022)

Disruption of NBS1/MRN Complex Formation by E4orf3 Supports NF-κB That Licenses E1B55K-Deleted Adenovirus-Infected Cells to Accumulate DNA>4n
por: Almuzaini, Nujud, et al.
Publicado: (2022)

Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia
por: Lai, Yandong, et al.
Publicado: (2021)

E4orf1 protein reduces the need for endogenous insulin
por: Peddibhotla, Swetha, et al.
Publicado: (2019)

A novel recombinant serotype 4 fowl adenovirus expressing fiber-2 protein of duck adenovirus 3
por: Guo, Yiwen, et al.
Publicado: (2023)

The adenoviral E4orf3/4 is a regulatory polypeptide with cell transforming properties in vitro
por: Ip, Wing-Hang, et al.
Publicado: (2023)

FLCN: A new regulator of AMPK-dependent Warburg metabolic reprogramming
por: Gingras, Marie-Claude, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_phv1apeq4j22d56hh37mad71lv