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BubR1 is essential for kinetochore localization of other spindle checkpoint proteins and its phosphorylation requires Mad1
The spindle checkpoint delays anaphase onset until all chromosomes have attached properly to the mitotic spindle. Checkpoint signal is generated at kinetochores that are not bound with spindle microtubules or not under tension. Unattached kinetochores associate with several checkpoint proteins, incl...
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173820/ https://www.ncbi.nlm.nih.gov/pubmed/12163471 http://dx.doi.org/10.1083/jcb.200204048 |