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c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation
Sympathetic neurons depend on NGF binding to TrkA for their survival during vertebrate development. NGF deprivation initiates a transcription-dependent apoptotic response, which is suggested to require activation of the transcription factor c-Jun. Similarly, apoptosis can also be induced by selectiv...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173823/ https://www.ncbi.nlm.nih.gov/pubmed/12163468 http://dx.doi.org/10.1083/jcb.200112129 |