Cargando…

c-jun is essential for sympathetic neuronal death induced by NGF withdrawal but not by p75 activation

Sympathetic neurons depend on NGF binding to TrkA for their survival during vertebrate development. NGF deprivation initiates a transcription-dependent apoptotic response, which is suggested to require activation of the transcription factor c-Jun. Similarly, apoptosis can also be induced by selectiv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Palmada, M., Kanwal, S., Rutkoski, N.J., Gustafson-Brown, C., Johnson, R.S., Wisdom, R., Carter, B.D.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173823/ https://www.ncbi.nlm.nih.gov/pubmed/12163468 http://dx.doi.org/10.1083/jcb.200112129

Ejemplares similares

Alternating metabolic pathways in NGF-deprived sympathetic neurons affect caspase-independent death
por: Chang, Louis K., et al.
Publicado: (2003)

The p75 Neurotrophin Receptor Mediates Neuronal Apoptosis and Is Essential for Naturally Occurring Sympathetic Neuron Death
por: Bamji, Shernaz X., et al.
Publicado: (1998)

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma
por: Marsland, Mark, et al.
Publicado: (2022)

Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death
por: Kristiansen, Mark, et al.
Publicado: (2011)

Stromal cell-derived NGF controls sympathetic innervation in subcutaneous fat
por: Meng, Xia, et al.
Publicado: (2022)

Axotomy-induced neurotrophic withdrawal causes the loss of phenotypic differentiation and downregulation of NGF signalling, but not death of septal cholinergic neurons
por: Lazo, Oscar M, et al.
Publicado: (2010)

Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition
por: Chang, Louis K., et al.
Publicado: (2002)

p75(NTR), but Not proNGF, Is Upregulated Following Status Epilepticus in Mice
por: VonDran, Melissa W., et al.
Publicado: (2014)

Systems Pharmacology of the NGF Signaling Through p75 and TrkA Receptors
por: Toni, T, et al.
Publicado: (2014)

ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75(NTR)-dependent mechanism
por: Howard, Laura, et al.
Publicado: (2013)

Non-canonical Ret signaling augments p75-mediated cell death in developing sympathetic neurons
por: Donnelly, Christopher R., et al.
Publicado: (2018)

Silencing p75(NTR) prevents proNGF-induced endothelial cell death and development of acellular capillaries in rat retina
por: Shanab, Ahmed Y, et al.
Publicado: (2015)

NGF-p75 signaling coordinates skeletal cell migration during bone repair
por: Xu, Jiajia, et al.
Publicado: (2022)

The Effect of Interaction NGF/p75(NTR) in Sperm Cells: A Rabbit Model
por: Castellini, Cesare, et al.
Publicado: (2022)

The NGF R100W Mutation, Associated with Hereditary Sensory Autonomic Neuropathy Type V, Specifically Affects the Binding Energetic Landscapes of NGF and of Its Precursor proNGF and p75NTR
por: Covaceuszach, Sonia, et al.
Publicado: (2023)

Genetic and metabolic status of NGF-deprived sympathetic neurons saved by an inhibitor of ICE family proteases
Publicado: (1996)

Viral proteins E1B19K and p35 protect sympathetic neurons from cell death induced by NGF deprivation
Publicado: (1995)

NGF and Neurotrophin-3 Both Activate TrkA on Sympathetic Neurons but Differentially Regulate Survival and Neuritogenesis
por: Belliveau, Daniel J., et al.
Publicado: (1997)

Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons
Publicado: (1992)

NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
por: Ruggeri, P, et al.
Publicado: (2016)

Characterization of NGF, trkA(NGFR), and p75(NTR) in Retina of Mice Lacking Reelin Glycoprotein
por: Balzamino, Bijorn Omar, et al.
Publicado: (2014)

QS8: The Roles of the TrkA and p75NTR NGF Receptors in Corneal Wound Healing
por: Tajdaran, Kiana, et al.
Publicado: (2021)

Age-induced nitrative stress decreases retrograde transport of proNGF via TrkA and increases proNGF retrograde transport and neurodegeneration via p75(NTR)
por: Kropf, Erika, et al.
Publicado: (2023)

Conjunctival reconstruction via enrichment of human conjunctival epithelial stem cells by p75 through the NGF‐p75‐SALL2 signaling axis
por: Wu, Nianxuan, et al.
Publicado: (2020)

The Release of Cytochrome c from Mitochondria during Apoptosis of NGF-deprived Sympathetic Neurons Is a Reversible Event
por: Martinou, Isabelle, et al.
Publicado: (1999)

Catheter Ablation of Atrial Fibrillation Raises the Plasma Level of NGF-β Which Is Associated with Sympathetic Nerve Activity
por: Park, Jae Hyung, et al.
Publicado: (2015)

Expression of Nerve Growth Factor (NGF), TrkA, and p75(NTR) in Developing Human Fetal Teeth
por: Mitsiadis, Thimios A., et al.
Publicado: (2016)

Targeted NGF siRNA Delivery Attenuates Sympathetic Nerve Sprouting and Deteriorates Cardiac Dysfunction in Rats with Myocardial Infarction
por: Hu, Hesheng, et al.
Publicado: (2014)

TrkA mediates developmental sympathetic neuron survival in vivo by silencing an ongoing p75NTR-mediated death signal
por: Majdan, Marta, et al.
Publicado: (2001)

A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75(NTR)-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo
por: Greenwood, Shayri G., et al.
Publicado: (2018)

NGF and P75(NTR) Gene Expression Is Associated with the Hepatic Fibrosis Stage Due to Viral and Non-Viral Causes
por: Amoras, Ednelza da Silva Graça, et al.
Publicado: (2015)

P75 and phosphorylated c-Jun are differentially regulated in spinal motoneurons following axotomy in rats☆
por: Yuan, Qiuju, et al.
Publicado: (2012)

Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal
Publicado: (1994)

Vagal Withdrawal and Sympathetic Overactivity Contribute to the Genesis of Early-Onset Pregnancy-Induced Hypertension
por: Pal, G. K., et al.
Publicado: (2011)

Cardiac Parasympathetic Withdrawal and Sympathetic Activity: Effect of Heat Exposure on Heart Rate Variability
por: Abellán-Aynés, Oriol, et al.
Publicado: (2021)

Cholinergic Degeneration and Alterations in the TrkA and p75NTR Balance as a Result of Pro-NGF Injection into Aged Rats
por: Fortress, Ashley M., et al.
Publicado: (2011)

Testicular Expression of NGF, TrkA and p75 During Seasonal Spermatogenesis of the Wild Ground Squirrel (Citellus Dauricus Brandt)
por: Zhang, H., et al.
Publicado: (2015)

Spatio-temporal expression profile of NGF and the two-receptor system, TrkA and p75NTR, in experimental autoimmune encephalomyelitis
por: Delivanoglou, Nickoleta, et al.
Publicado: (2020)

Downregulation of OIP5-AS1 affects proNGF-induced pancreatic cancer metastasis by inhibiting p75NTR levels
por: Li, Ang, et al.
Publicado: (2021)

NGF/TRKA Promotes ADAM17-Dependent Cleavage of P75 in Ovarian Cells: Elucidating a Pro-Tumoral Mechanism
por: Garrido, Maritza P., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3402eouqabu1ngq4edhdru3o8j