Cargando…

The contribution of peroxynitrite generation in HIV replication in human primary macrophages

BACKGROUND: Monocytes/Macrophages (M/M) play a pivotal role as a source of virus during the whole course of HIV-1 infection. Enhanced oxidative stress is involved in the pathogenesis of HIV-1 infection. HIV-1 regulatory proteins induce a reduction of the expression and the activity of MnSOD, the mit...

Descripción completa

Detalles Bibliográficos
Autores principales: Aquaro, Stefano, Muscoli, Carolina, Ranazzi, Alessandro, Pollicita, Michela, Granato, Teresa, Masuelli, Laura, Modesti, Andrea, Perno, Carlo-Federico, Mollace, Vincenzo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173904/
https://www.ncbi.nlm.nih.gov/pubmed/17949509
http://dx.doi.org/10.1186/1742-4690-4-76