Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells

Botulinum neurotoxins (BoNTs) cause botulism by entering neurons and cleaving proteins that mediate neurotransmitter release; disruption of exocytosis results in paralysis and death. The receptors for BoNTs are thought to be composed of both proteins and gangliosides; however, protein components tha...

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Detalles Bibliográficos
Autores principales: Dong, Min, Richards, David A., Goodnough, Michael C., Tepp, William H., Johnson, Eric A., Chapman, Edwin R.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173968/
https://www.ncbi.nlm.nih.gov/pubmed/14504267
http://dx.doi.org/10.1083/jcb.200305098

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