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RhoA/ROCK regulation of neuritogenesis via profilin IIa–mediated control of actin stability

Neuritogenesis, the first step of neuronal differentiation, takes place as nascent neurites bud from the immediate postmitotic neuronal soma. Little is known about the mechanisms underlying the dramatic morphological changes that characterize this event. Here, we show that RhoA activity plays a deci...

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Detalles Bibliográficos
Autores principales: Da Silva, Jorge Santos, Medina, Miguel, Zuliani, Cecilia, Di Nardo, Alessia, Witke, Walter, Dotti, Carlos G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173969/
https://www.ncbi.nlm.nih.gov/pubmed/14517206
http://dx.doi.org/10.1083/jcb.200304021