Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT

Ghrelin is an acyl-peptide gastric hormone acting on the pituitary and hypothalamus to stimulate growth hormone (GH) release, adiposity, and appetite. Ghrelin endocrine activities are entirely dependent on its acylation and are mediated by GH secretagogue (GHS) receptor (GHSR)-1a, a G protein–couple...

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Detalles Bibliográficos
Autores principales: Baldanzi, Gianluca, Filigheddu, Nicoletta, Cutrupi, Santina, Catapano, Filomena, Bonissoni, Sara, Fubini, Alberto, Malan, Daniela, Baj, Germano, Granata, Riccarda, Broglio, Fabio, Papotti, Mauro, Surico, Nicola, Bussolino, Federico, Isgaard, Jorgen, Deghenghi, Romano, Sinigaglia, Fabiola, Prat, Maria, Muccioli, Giampiero, Ghigo, Ezio, Graziani, Andrea
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173981/
https://www.ncbi.nlm.nih.gov/pubmed/12486113
http://dx.doi.org/10.1083/jcb.200207165

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