A survival pathway for Caenorhabditis elegans with a blocked unfolded protein response

The unfolded protein response (UPR) counteracts stress caused by unprocessed ER client proteins. A genome-wide survey showed impaired induction of many UPR target genes in xbp-1 mutant Caenorhabditis elegans that are unable to signal in the highly conserved IRE1-dependent UPR pathway. However a fami...

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Detalles Bibliográficos
Autores principales: Urano, Fumihiko, Calfon, Marcella, Yoneda, Takunari, Yun, Chi, Kiraly, Moni, Clark, Scott G., Ron, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174003/
https://www.ncbi.nlm.nih.gov/pubmed/12186849
http://dx.doi.org/10.1083/jcb.200203086

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