Sweet solution: sugars to the rescue

Sugar pills are usually placebos, but Smith et al. (2002, this issue) use one to rescue designer mice unable to make GDP-Fucose. Dietary fucose enters a salvage pathway and spares the mice. Sound simple? Not so. Unknown genetic factors determine life or death.

Detalles Bibliográficos
Autor principal: Freeze, Hudson H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174005/
https://www.ncbi.nlm.nih.gov/pubmed/12186848
http://dx.doi.org/10.1083/jcb.200207155
Descripción
Sumario:Sugar pills are usually placebos, but Smith et al. (2002, this issue) use one to rescue designer mice unable to make GDP-Fucose. Dietary fucose enters a salvage pathway and spares the mice. Sound simple? Not so. Unknown genetic factors determine life or death.

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