The adenomatous polyposis coli protein unambiguously localizes to microtubule plus ends and is involved in establishing parallel arrays of microtubule bundles in highly polarized epithelial cells

Loss of full-length adenomatous polyposis coli (APC) protein correlates with the development of colon cancers in familial and sporadic cases. In addition to its role in regulating β-catenin levels in the Wnt signaling pathway, the APC protein is implicated in regulating cytoskeletal organization. AP...

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Detalles Bibliográficos
Autores principales: Mogensen, Mette M., Tucker, John B., Mackie, John B., Prescott, Alan R., Näthke, Inke S.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174057/
https://www.ncbi.nlm.nih.gov/pubmed/12058019
http://dx.doi.org/10.1083/jcb.200203001

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