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Human Cyclin a Is Required for Mitosis until Mid Prophase

We have used microinjection and time-lapse video microscopy to study the role of cyclin A in mitosis. We have injected purified, active cyclin A/cyclin-dependent kinase 2 (CDK2) into synchronized cells at specific points in the cell cycle and assayed its effect on cell division. We find that cyclin...

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Detalles Bibliográficos
Autores principales: Furuno, Nobuaki, den Elzen, Nicole, Pines, Jonathon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174228/
https://www.ncbi.nlm.nih.gov/pubmed/10525536