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Cholera Toxin Is Exported from Microsomes by the Sec61p Complex

After endocytosis cholera toxin is transported to the endoplasmic reticulum (ER), from where its A1 subunit (CTA1) is assumed to be transferred to the cytosol by an as-yet unknown mechanism. Here, export of CTA1 from the ER to the cytosol was investigated in a cell-free assay using either microsomes...

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Detalles Bibliográficos
Autores principales: Schmitz, Anton, Herrgen, Helga, Winkeler, Alexandra, Herzog, Volker
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174307/
https://www.ncbi.nlm.nih.gov/pubmed/10725333