Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas in Transgenic Mice

Overexpression is the most common abnormality of receptor tyrosine kinases (RTKs) in human tumors. It is presumed that overexpression leads to constitutive activation of RTKs, but the mechanism of that activation has been uncertain. Here we show that overexpression of the Met RTK allows activation o...

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Detalles Bibliográficos
Autores principales: Wang, Rong, Ferrell, Linda D., Faouzi, Saadia, Maher, Jacquelyn J., Bishop, J. Michael
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174327/
https://www.ncbi.nlm.nih.gov/pubmed/11381087

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