Cyclin-Dependent Kinase Inhibitor P27(Kip1) Is Required for Mouse Mammary Gland Morphogenesis and Function

We have studied the role of the cyclin-dependent kinase (Cdk) inhibitor p27(Kip1) in postnatal mammary gland morphogenesis. Based on its ability to negatively regulate cyclin/Cdk function, loss of p27 may result in unrestrained cellular proliferation. However, recent evidence about the stabilizing e...

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Detalles Bibliográficos
Autores principales: Muraoka, Rebecca S., Lenferink, Anne E.G., Simpson, Jean, Brantley, Dana M., Roebuck, L. Renee, Yakes, F. Michael, Arteaga, Carlos L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174338/
https://www.ncbi.nlm.nih.gov/pubmed/11381079

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