Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

Phosphorylation of the α subunit of eukaryotic translation initiation factor 2 (eIF2α) on serine 51 integrates general translation repression with activation of stress-inducible genes such as ATF4, CHOP, and BiP in the unfolded protein response. We sought to identify new genes active in this phospho...

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Detalles Bibliográficos
Autores principales: Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174339/
https://www.ncbi.nlm.nih.gov/pubmed/11381086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174339/
https://www.ncbi.nlm.nih.gov/pubmed/11381086

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