Mutagenesis of the Phosphatidylinositol 4,5-Bisphosphate (Pip(2)) Binding Site in the Nh(2)-Terminal Domain of Ezrin Correlates with Its Altered Cellular Distribution

The cytoskeleton-membrane linker protein ezrin has been shown to associate with phosphatidyl-inositol 4,5-bisphosphate (PIP(2))-containing liposomes via its NH(2)-terminal domain. Using internal deletions and COOH-terminal truncations, determinants of PIP(2) binding were located to amino acids 12–11...

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Detalles Bibliográficos
Autores principales: Barret, Cécile, Roy, Christian, Montcourrier, Philippe, Mangeat, Paul, Niggli, Verena
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174347/
https://www.ncbi.nlm.nih.gov/pubmed/11086008

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