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Epitope-Tagged P(0)Glycoprotein Causes Charcot-Marie-Tooth–Like Neuropathy in Transgenic Mice
In peripheral nerve myelin, the intraperiod line results from compaction of the extracellular space due to homophilic adhesion between extracellular domains (ECD) of the protein zero (P(0)) glycoprotein. Point mutations in this region of P(0) cause human hereditary demyelinating neuropathies such as...
Autores principales: | Previtali, Stefano C., Quattrini, Angelo, Fasolini, Marina, Panzeri, Maria Carla, Villa, Antonello, Filbin, Marie T., Li, Wenhui, Chiu, Shing-Yan, Messing, Albee, Wrabetz, Lawrence, Feltri, M. Laura |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174348/ https://www.ncbi.nlm.nih.gov/pubmed/11086005 |
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