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Caspases Disrupt the Nuclear-Cytoplasmic Barrier
During apoptosis, caspases, a family of proteases, disassemble a cell by cleaving a set of proteins. Caspase-3 plays a major role in the disassembly of the nucleus by processing several nuclear substrates. The question is how caspase-3, which is usually cytoplasmic, gains access to its nuclear targe...
Autores principales: | Faleiro, Lavina, Lazebnik, Yuri |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174353/ https://www.ncbi.nlm.nih.gov/pubmed/11085998 |
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