Ablation of Uroplakin III Gene Results in Small Urothelial Plaques, Urothelial Leakage, and Vesicoureteral Reflux

Urothelium synthesizes a group of integral membrane proteins called uroplakins, which form two-dimensional crystals (urothelial plaques) covering >90% of the apical urothelial surface. We show that the ablation of the mouse uroplakin III (UPIII) gene leads to overexpression, defective glycosylati...

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Detalles Bibliográficos
Autores principales: Hu, Ping, Deng, Fang-Ming, Liang, Feng-Xia, Hu, Chuan-Min, Auerbach, Anna B., Shapiro, Ellen, Wu, Xue-Ru, Kachar, Bechara, Sun, Tung-Tien
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174354/
https://www.ncbi.nlm.nih.gov/pubmed/11085999

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