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Optimal ex vivo expansion of neutrophils from PBSC CD34(+ )cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO

BACKGROUND: Autologous mobilised peripheral blood stem cell (PBSC) transplantation is now a standard approach in the treatment of haematological diseases to reconstitute haematopoiesis following myeloablative chemotherapy. However, there remains a period of severe neutropenia and thrombocytopenia be...

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Detalles Bibliográficos
Autores principales:	Tura, Olga, Barclay, G Robin, Roddie, Huw, Davies, John, Turner, Marc L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174439/ https://www.ncbi.nlm.nih.gov/pubmed/17971220 http://dx.doi.org/10.1186/1479-5876-5-53

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