Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

BRCA1 has been implicated in numerous DNA repair pathways that maintain genome integrity, however the function responsible for its tumor suppressor activity in breast cancer remains obscure. To identify the most highly conserved of the many BRCA1 functions, we screened the evolutionarily distant euk...

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Detalles Bibliográficos
Autores principales: Bennett, Craig B., Westmoreland, Tammy J., Verrier, Carmel S., Blanchette, Carrie A. B., Sabin, Tiffany L., Phatnani, Hemali P., Mishina, Yuliya V., Huper, Gudrun, Selim, Alice L., Madison, Ernest R., Bailey, Dominique D., Falae, Adebola I., Galli, Alvaro, Olson, John A., Greenleaf, Arno L., Marks, Jeffrey R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174531/
https://www.ncbi.nlm.nih.gov/pubmed/18197258
http://dx.doi.org/10.1371/journal.pone.0001448

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