Cargando…
MAD3 Encodes a Novel Component of the Spindle Checkpoint Which Interacts with Bub3p, Cdc20p, and Mad2p
We show that MAD3 encodes a novel 58-kD nuclear protein which is not essential for viability, but is an integral component of the spindle checkpoint in budding yeast. Sequence analysis reveals two regions of Mad3p that are 46 and 47% identical to sequences in the NH(2)-terminal region of the budding...
Autores principales: | Hardwick, Kevin G., Johnston, Raymond C., Smith, Dana L., Murray, Andrew W. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174553/ https://www.ncbi.nlm.nih.gov/pubmed/10704439 |
Ejemplares similares
-
Mad3 KEN Boxes Mediate both Cdc20 and Mad3 Turnover, and Are Critical for the Spindle Checkpoint
por: King, Emma M.J., et al.
Publicado: (2007) -
The Spindle Checkpoint Functions of Mad3 and Mad2 Depend on a Mad3 KEN Box-mediated Interaction with Cdc20-Anaphase-promoting Complex (APC/C)
por: Sczaniecka, Matylda, et al.
Publicado: (2008) -
The Bub1-TPR Domain Interacts Directly with Mad3 to Generate Robust Spindle Checkpoint Arrest
por: Leontiou, Ioanna, et al.
Publicado: (2019) -
Spindle Checkpoint Protein Bub1 Is Required for Kinetochore Localization of Mad1, Mad2, Bub3, and Cenp-E, Independently of Its Kinase Activity
por: Sharp-Baker, Hilary, et al.
Publicado: (2001) -
A Bub1–Mad1 interaction targets the Mad1–Mad2 complex to unattached kinetochores to initiate the spindle checkpoint
por: Moyle, Mark W., et al.
Publicado: (2014)