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A map of human cancer signaling

We conducted a comprehensive analysis of a manually curated human signaling network containing 1634 nodes and 5089 signaling regulatory relations by integrating cancer-associated genetically and epigenetically altered genes. We find that cancer mutated genes are enriched in positive signaling regula...

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Detalles Bibliográficos
Autores principales: Cui, Qinghua, Ma, Yun, Jaramillo, Maria, Bari, Hamza, Awan, Arif, Yang, Song, Zhang, Simo, Liu, Lixue, Lu, Meng, O'Connor-McCourt, Maureen, Purisima, Enrico O, Wang, Edwin
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174632/
https://www.ncbi.nlm.nih.gov/pubmed/18091723
http://dx.doi.org/10.1038/msb4100200