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Cdc42 and Rac Stimulate Exocytosis of Secretory Granules by Activating the Ip(3)/Calcium Pathway in Rbl-2h3 Mast Cells
We have expressed dominant-active and dominant-negative forms of the Rho GTPases, Cdc42 and Rac, using vaccinia virus to evaluate the effects of these mutants on the signaling pathway leading to the degranulation of secretory granules in RBL-2H3 cells. Dominant-active Cdc42 and Rac enhance antigen-s...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174803/ https://www.ncbi.nlm.nih.gov/pubmed/10662774 |