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The Drosophila Perlecan gene trol regulates multiple signaling pathways in different developmental contexts

BACKGROUND: Heparan sulfate proteoglycans modulate signaling by a variety of growth factors. The mammalian proteoglycan Perlecan binds and regulates signaling by Sonic Hedgehog, Fibroblast Growth Factors (FGFs), Vascular Endothelial Growth Factor (VEGF) and Platelet Derived Growth Factor (PDGF), amo...

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Detalles Bibliográficos
Autores principales:	Lindner, Jonathan R, Hillman, Paul R, Barrett, Andrea L, Jackson, Megan C, Perry, Trinity L, Park, Youngji, Datta, Sumana
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174950/ https://www.ncbi.nlm.nih.gov/pubmed/17980035 http://dx.doi.org/10.1186/1471-213X-7-121

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