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The Role of the Cooh Terminus of Sec2p in the Transport of Post-Golgi Vesicles

Sec2p is required for the polarized transport of secretory vesicles in S. cerevisiae. The Sec2p NH(2) terminus encodes an exchange factor for the Rab protein Sec4p. Sec2p associates with vesicles and in Sec2p COOH-terminal mutants Sec4p and vesicles no longer accumulate at bud tips. Thus, the Sec2p...

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Detalles Bibliográficos
Autores principales:	Elkind, N. Barry, Walch-Solimena, Christiane, Novick, Peter J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175086/ https://www.ncbi.nlm.nih.gov/pubmed/10747090

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