Orbit, a Novel Microtubule-Associated Protein Essential for Mitosis in Drosophila melanogaster

We describe a Drosophila gene, orbit, that encodes a conserved 165-kD microtubule-associated protein (MAP) with GTP binding motifs. Hypomorphic mutations in orbit lead to a maternal effect resulting in branched and bent mitotic spindles in the syncytial embryo. In the larval central nervous system,...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoue, Yoshihiro H., do Carmo Avides, Maria, Shiraki, Michina, Deak, Peter, Yamaguchi, Masamitsu, Nishimoto, Yoshio, Matsukage, Akio, Glover, David M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175100/
https://www.ncbi.nlm.nih.gov/pubmed/10747094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175100/
https://www.ncbi.nlm.nih.gov/pubmed/10747094

Ejemplares similares