The Tyrosine Kinase Pyk-2/Raftk Regulates Natural Killer (Nk) Cell Cytotoxic Response, and Is Translocated and Activated upon Specific Target Cell Recognition and Killing

The compartmentalization of plasma membrane proteins has a key role in regulation of lymphocyte activation and development of immunity. We found that the proline-rich tyrosine kinase-2 (PYK-2/RAFTK) colocalized with the microtubule-organizing center (MTOC) at the trailing edge of migrating natural k...

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Detalles Bibliográficos
Autores principales: Sancho, David, Nieto, Marta, Llano, Manuel, Rodríguez-Fernández, José L., Tejedor, Reyes, Avraham, Shalom, Cabañas, Carlos, López-Botet, Miguel, Sánchez-Madrid, Francisco
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
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Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175114/
https://www.ncbi.nlm.nih.gov/pubmed/10851022

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