Apical Membrane Targeting of Nedd4 Is Mediated by an Association of Its C2 Domain with Annexin Xiiib

Nedd4 is a ubiquitin protein ligase (E3) containing a C2 domain, three or four WW domains, and a ubiquitin ligase HECT domain. We have shown previously that the C2 domain of Nedd4 is responsible for its Ca(2+)-dependent targeting to the plasma membrane, particularly the apical region of epithelial M...

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Detalles Bibliográficos
Autores principales: Plant, Pamela J., Lafont, Frank, Lecat, Sandra, Verkade, Paul, Simons, Kai, Rotin, Daniela
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175132/
https://www.ncbi.nlm.nih.gov/pubmed/10871286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175132/
https://www.ncbi.nlm.nih.gov/pubmed/10871286

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