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Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses

Gab1 is a substrate of the receptor tyrosine kinase c-Met and involved in c-Met–specific branching morphogenesis. It associates directly with c-Met via the c-Met–binding domain, which is not related to known phosphotyrosine-binding domains. In addition, Gab1 is engaged in a constitutive complex with...

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Detalles Bibliográficos
Autores principales: Schaeper, Ute, Gehring, Niels H., Fuchs, Klaus P., Sachs, Martin, Kempkes, Bettina, Birchmeier, Walter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175135/
https://www.ncbi.nlm.nih.gov/pubmed/10871282