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Coupling of Gab1 to C-Met, Grb2, and Shp2 Mediates Biological Responses
Gab1 is a substrate of the receptor tyrosine kinase c-Met and involved in c-Met–specific branching morphogenesis. It associates directly with c-Met via the c-Met–binding domain, which is not related to known phosphotyrosine-binding domains. In addition, Gab1 is engaged in a constitutive complex with...
Autores principales: | Schaeper, Ute, Gehring, Niels H., Fuchs, Klaus P., Sachs, Martin, Kempkes, Bettina, Birchmeier, Walter |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175135/ https://www.ncbi.nlm.nih.gov/pubmed/10871282 |
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