Cargando…

Phosphorylation by Cdc28 Activates the Cdc20-Dependent Activity of the Anaphase-Promoting Complex

Budding yeast initiates anaphase by activating the Cdc20-dependent anaphase-promoting complex (APC). The mitotic activity of Cdc28 (Cdk1) is required to activate this form of the APC, and mutants that are impaired in mitotic Cdc28 function have difficulty leaving mitosis. This defect can be explaine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rudner, Adam D., Murray, Andrew W.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2000
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175139/ https://www.ncbi.nlm.nih.gov/pubmed/10871279

Ejemplares similares

Cdc28 Activates Exit from Mitosis in Budding Yeast
por: Rudner, Adam D., et al.
Publicado: (2000)

Ama1p-activated anaphase-promoting complex regulates the destruction of Cdc20p during meiosis II
por: Tan, Grace S., et al.
Publicado: (2011)

Activity of the APC(Cdh1) form of the anaphase-promoting complex persists until S phase and prevents the premature expression of Cdc20p
por: Huang, James N., et al.
Publicado: (2001)

PP1 promotes cyclin B destruction and the metaphase–anaphase transition by dephosphorylating CDC20
por: Bancroft, James, et al.
Publicado: (2020)

Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex
por: Paul, Debasish, et al.
Publicado: (2017)

Cdc14-regulated midzone assembly controls anaphase B
por: Khmelinskii, Anton, et al.
Publicado: (2007)

Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae
por: Yang, Yang, et al.
Publicado: (2015)

Regulation of APC/C(Cdc20) activity by RASSF1A–APC/C(Cdc20) circuitry
por: Chow, C, et al.
Publicado: (2012)

Identification of the C. elegans anaphase promoting complex subunit Cdc26 by phenotypic profiling and functional rescue in yeast
por: Dong, Yan, et al.
Publicado: (2007)

Insights into Anaphase Promoting Complex TPR subdomain assembly from a CDC26–APC6 structure
por: Wang, Jing, et al.
Publicado: (2009)

Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase
por: Queralt, Ethel, et al.
Publicado: (2008)

The Spindle Checkpoint Functions of Mad3 and Mad2 Depend on a Mad3 KEN Box-mediated Interaction with Cdc20-Anaphase-promoting Complex (APC/C)
por: Sczaniecka, Matylda, et al.
Publicado: (2008)

APC/C(Cdc20)-mediated degradation of Clb4 prompts astral microtubule stabilization at anaphase onset
por: Zucca, Federico, et al.
Publicado: (2022)

Anaphase-promoting complex/cyclosome protein Cdc27 is a target for curcumin-induced cell cycle arrest and apoptosis
por: Lee, Seung Joon, et al.
Publicado: (2012)

The Bub1–Plk1 kinase complex promotes spindle checkpoint signalling through Cdc20 phosphorylation
por: Jia, Luying, et al.
Publicado: (2016)

Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication
por: Chang, FuJung, et al.
Publicado: (2015)

Mammalian p55CDC Mediates Association of the Spindle Checkpoint Protein Mad2 with the Cyclosome/Anaphase-promoting Complex, and is Involved in Regulating Anaphase Onset and Late Mitotic Events
por: Kallio, Marko, et al.
Publicado: (1998)

Cdc18/CDC6 activates the Rad3-dependent checkpoint in the fission yeast
por: Fersht, Naomi, et al.
Publicado: (2007)

Role of phosphorylation of Cdc20 in the regulation of the action of APC/C in mitosis
por: Shevah-Sitry, Danielle, et al.
Publicado: (2022)

Doing the CDC20 shuffle
por: Wells, William A.
Publicado: (2003)

Deregulated Cdc6 inhibits DNA replication and suppresses Cdc7-mediated phosphorylation of Mcm2–7 complex
por: Kundu, Lena R., et al.
Publicado: (2010)

Coupling of Cdc20 inhibition and activation by BubR1
por: Hein, Jamin B., et al.
Publicado: (2021)

Cdc14 Early Anaphase Release, FEAR, Is Limited to the Nucleus and Dispensable for Efficient Mitotic Exit
por: Yellman, Christopher M., et al.
Publicado: (2015)

Juxtaposition of Bub1 and Cdc20 on phosphorylated Mad1 during catalytic mitotic checkpoint complex assembly
por: Fischer, Elyse S., et al.
Publicado: (2022)

Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest
por: May, Karen M., et al.
Publicado: (2017)

Cdc5 influences phosphorylation of Net1 and disassembly of the RENT complex
por: Shou, Wenying, et al.
Publicado: (2002)

Raptor is Phosphorylated by cdc2 during Mitosis
por: Gwinn, Dana M., et al.
Publicado: (2010)

Phosphorylation of Cdc5 regulates its accumulation
por: Simpson-Lavy, Kobi J, et al.
Publicado: (2011)

The Mitotic Checkpoint Complex binds a second CDC20 to inhibit active APC/C
por: Izawa, Daisuke, et al.
Publicado: (2014)

Adaptation to the spindle checkpoint is regulated by the interplay between Cdc28/Clbs and PP2A(Cdc55)
por: Vernieri, Claudio, et al.
Publicado: (2013)

Saccharomyces cerevisiae deficient in the early anaphase release of Cdc14 can traverse anaphase I without ribosomal DNA disjunction and successfully complete meiosis
por: Yellman, Christopher M.
Publicado: (2023)

High levels of histones promote whole-genome-duplications and trigger a Swe1(WEE1)-dependent phosphorylation of Cdc28(CDK1)
por: Maya Miles, Douglas, et al.
Publicado: (2018)

Functional analysis of recurrent CDC20 promoter variants in human melanoma
por: Godoy, Paula M., et al.
Publicado: (2023)

Cdc42 interacts with the exocyst complex to promote phagocytosis
por: Mohammadi, Sina, et al.
Publicado: (2013)

Regulated degradation of the APC coactivator Cdc20
por: Robbins, Jonathan A, et al.
Publicado: (2010)

CDC20 maintains tumor initiating cells
por: Xie, Qi, et al.
Publicado: (2015)

Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13
por: Tseng, Shun-Fu, et al.
Publicado: (2009)

CDC Surveillance Strategy – A Strategy for Improving CDC Activities in Public Health Surveillance
por: Richards, Chesley, et al.
Publicado: (2015)

Nonredundant Requirement for Multiple Histone Modifications for the Early Anaphase Release of the Mitotic Exit Regulator Cdc14 from Nucleolar Chromatin
por: Hwang, William W., et al.
Publicado: (2009)

Caffeine as a tool for investigating the integration of Cdc25 phosphorylation, activity and ubiquitin-dependent degradation in Schizosaccharomyces pombe
por: Alao, John P., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2ebc33v95v7oj9ftv4klgf99k5