Autocrine Tumor Necrosis Factor (TNF) and Lymphotoxin (LT) α Differentially Modulate Cellular Sensitivity to TNF/LT-α Cytotoxicity in L929 Cells

Tumor necrosis factor (TNF) and lymphotoxin (LT) α are structurally and functionally related cytokines. We expressed the TNF and LT-α genes in murine fibrosarcoma L929r2 cells, which can be sensitized to TNF/LT-α–dependent necrosis by inhibitors of transcription or translation. Autocrine production...

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Detalles Bibliográficos
Autores principales: Decoster, Els, Cornelis, Sigrid, Vanhaesebroeck, Bart, Fiers, Walter
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175230/
https://www.ncbi.nlm.nih.gov/pubmed/9864375

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