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Atrophin-1, the Dentato-Rubral and Pallido-Luysian Atrophy Gene Product, Interacts with Eto/Mtg8 in the Nuclear Matrix and Represses Transcription
Dentato-rubral and pallido-luysian atrophy (DRPLA) is one of the family of neurodegenerative diseases caused by expansion of a polyglutamine tract. The drpla gene product, atrophin-1, is widely expressed, has no known function or activity, and is found in both the nuclear and cytoplasmic compartment...
Autores principales: | Wood, Jonathan D., Nucifora, Frederick C., Duan, Kui, Zhang, Chuanyi, Wang, Jianxiang, Kim, Yujin, Schilling, Gabriele, Sacchi, Nicoletta, Liu, Johnson M., Ross, Christopher A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175251/ https://www.ncbi.nlm.nih.gov/pubmed/10973986 |
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