Changes in Endoplasmic Reticulum Luminal Environment Affect Cell Sensitivity to Apoptosis

To test the role of ER luminal environment in apoptosis, we generated HeLa cell lines inducible with respect to calreticulin and calnexin and investigated their sensitivity to drug-dependent apoptosis. Overexpression of calreticulin, an ER luminal protein, resulted in an increased sensitivity of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakamura, Kimitoshi, Bossy-Wetzel, Ella, Burns, Kimberly, Fadel, Marc P., Lozyk, Mira, Goping, Ing Swie, Opas, Michal, Bleackley, R. Chris, Green, Douglas R., Michalak, Marek
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2175288/
https://www.ncbi.nlm.nih.gov/pubmed/10952999

Ejemplares similares

Ejemplares similares